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Home > Blog > Case > Biopharma-Cleanroom System Solution

Biopharma-Cleanroom System Solution

May 21, 2025

Client Profile

Enterprise: Listed biopharmaceutical company
Core Products: Injectable biologics/IVD reagents
Project Scope: Class 100,000 cleanroom complex

Technical Implementation

Class 100,000 Area

Module	Technical Components
Air Filtration	H13 HEPA + Desiccant dehumidifier
Pressure Control	Cascading differential pressure
Airflow Pattern	Top-down supply with side returns
Surface Materials	Antimicrobial epoxy flooring

BSL Area

Safety Feature	Implementation
Containment	-15Pa negative pressure
Airlock	Double-door pass-through with VHP
Exhaust Treatment	Dual HEPA + Thermal inactivation

PCR Lab

Functional Zone	Environmental Control
Reagent Prep	Class 10,000 + Laminar flow hood
Sample Handling	Dedicated exhaust + UV disinfection
Amplification	Unidirectional airflow design

Technical Features

Cross-Contamination Prevention
- Material pass-through interlock
- Buffer zone pressure monitoring
Predictive Maintenance
- Filter resistance trend analysis
- Automatic fan redundancy activation
Energy Optimization
- Nighttime low-power operation
- Heat recovery system integration